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587 results

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Page 1
Did you mean gm csf and connective tissue (283 results)?
Osteoblast-Osteoclast Communication and Bone Homeostasis.
Kim JM, Lin C, Stavre Z, Greenblatt MB, Shim JH. Kim JM, et al. Cells. 2020 Sep 10;9(9):2073. doi: 10.3390/cells9092073. Cells. 2020. PMID: 32927921 Free PMC article. Review.
Alternatively, osteoblasts produce a range of different secretory molecules, including M-CSF, RANKL/OPG, WNT5A, and WNT16, that promote or suppress osteoclast differentiation and development. ...
Alternatively, osteoblasts produce a range of different secretory molecules, including M-CSF, RANKL/OPG, WNT5A, and WNT16, tha …
Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation.
Fabre T, Barron AMS, Christensen SM, Asano S, Bound K, Lech MP, Wadsworth MH 2nd, Chen X, Wang C, Wang J, McMahon J, Schlerman F, White A, Kravarik KM, Fisher AJ, Borthwick LA, Hart KM, Henderson NC, Wynn TA, Dower K. Fabre T, et al. Sci Immunol. 2023 Apr 14;8(82):eadd8945. doi: 10.1126/sciimmunol.add8945. Epub 2023 Apr 7. Sci Immunol. 2023. PMID: 37027478
Macrophages are central orchestrators of the tissue response to injury, with distinct macrophage activation states playing key roles in fibrosis progression and resolution. Identifying key macrophage populations found in human fibrotic tissues could lead to n …
Macrophages are central orchestrators of the tissue response to injury, with distinct macrophage activation states playing key …
Growth factors and cytokines in wound healing.
Barrientos S, Stojadinovic O, Golinko MS, Brem H, Tomic-Canic M. Barrientos S, et al. Wound Repair Regen. 2008 Sep-Oct;16(5):585-601. doi: 10.1111/j.1524-475X.2008.00410.x. Wound Repair Regen. 2008. PMID: 19128254 Review.
The migration, infiltration, proliferation, and differentiation of these cells will culminate in an inflammatory response, the formation of new tissue and ultimately wound closure. This complex process is executed and regulated by an equally complex signaling network invol …
The migration, infiltration, proliferation, and differentiation of these cells will culminate in an inflammatory response, the formation of …
Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy.
Cannarile MA, Weisser M, Jacob W, Jegg AM, Ries CH, Rüttinger D. Cannarile MA, et al. J Immunother Cancer. 2017 Jul 18;5(1):53. doi: 10.1186/s40425-017-0257-y. J Immunother Cancer. 2017. PMID: 28716061 Free PMC article. Review.
The tumor-permissive and immunosuppressive characteristics of tumor-associated macrophages (TAM) have fueled interest in therapeutically targeting these cells. In this context, the colony-stimulating factor 1 (CSF1)/colony-stimulating factor …
The tumor-permissive and immunosuppressive characteristics of tumor-associated macrophages (TAM) have fueled interest in therapeutically tar …
Evaluation of efficacy on RANKL induced osteoclast from RAW264.7 cells.
Song C, Yang X, Lei Y, Zhang Z, Smith W, Yan J, Kong L. Song C, et al. J Cell Physiol. 2019 Jul;234(7):11969-11975. doi: 10.1002/jcp.27852. Epub 2018 Dec 4. J Cell Physiol. 2019. PMID: 30515780
Therefore, in the current study, we examined the efficacy of various concentrations of RANKL-treated RAW264.7 for its osteoclastic differentiation with or without pretreated other costimulators such as: LPS and/or M-CSF. The oteoclastogenesis ability of RANKL-treate …
Therefore, in the current study, we examined the efficacy of various concentrations of RANKL-treated RAW264.7 for its osteoclastic different …
Aged skeletal stem cells generate an inflammatory degenerative niche.
Ambrosi TH, Marecic O, McArdle A, Sinha R, Gulati GS, Tong X, Wang Y, Steininger HM, Hoover MY, Koepke LS, Murphy MP, Sokol J, Seo EY, Tevlin R, Lopez M, Brewer RE, Mascharak S, Lu L, Ajanaku O, Conley SD, Seita J, Morri M, Neff NF, Sahoo D, Yang F, Weissman IL, Longaker MT, Chan CKF. Ambrosi TH, et al. Nature. 2021 Sep;597(7875):256-262. doi: 10.1038/s41586-021-03795-7. Epub 2021 Aug 11. Nature. 2021. PMID: 34381212 Free PMC article.
Diet-regulated production of PDGFcc by macrophages controls energy storage.
Cox N, Crozet L, Holtman IR, Loyher PL, Lazarov T, White JB, Mass E, Stanley ER, Elemento O, Glass CK, Geissmann F. Cox N, et al. Science. 2021 Jul 2;373(6550):eabe9383. doi: 10.1126/science.abe9383. Science. 2021. PMID: 34210853 Free PMC article.
The mechanisms by which macrophages regulate energy storage remain poorly understood. We identify in a genetic screen a platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF)-family ortholog, Pvf3, that is produced by macrophages and is requ …
The mechanisms by which macrophages regulate energy storage remain poorly understood. We identify in a genetic screen a platelet-derived gro …
Adipose-derived cells.
Meliga E, Strem BM, Duckers HJ, Serruys PW. Meliga E, et al. Cell Transplant. 2007;16(9):963-70. doi: 10.3727/096368907783338190. Cell Transplant. 2007. PMID: 18293895 Free article. Review.
ADSCs express multiple CD marker antigens similar to those observed on MSCs and are also capable of secreting a large number of angiogenesis-related cytokines, including vascular endothelial growth factor, granulocyte/macrophage colony stimulating f …
ADSCs express multiple CD marker antigens similar to those observed on MSCs and are also capable of secreting a large number of angiogenesis …
Osteoporosis and inflammation.
Lacativa PG, Farias ML. Lacativa PG, et al. Arq Bras Endocrinol Metabol. 2010 Mar;54(2):123-32. doi: 10.1590/s0004-27302010000200007. Arq Bras Endocrinol Metabol. 2010. PMID: 20485900 Review.
Several inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, celiac disease, cystic fibrosis and chronic obstructive pulmonary disease have been associated to bone resorption. The link between osteoclast, macrophage …
Several inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, celiac disease, cystic …
M-CSF priming of osteoclast precursors can cause osteoclastogenesis-insensitivity, which can be prevented and overcome on bone.
De Vries TJ, Schoenmaker T, Aerts D, Grevers LC, Souza PP, Nazmi K, van de Wiel M, Ylstra B, Lent PL, Leenen PJ, Everts V. De Vries TJ, et al. J Cell Physiol. 2015 Jan;230(1):210-25. doi: 10.1002/jcp.24702. J Cell Physiol. 2015. PMID: 24962140
Osteoclasts and macrophages share progenitors that must receive decisive lineage signals driving them into their respective differentiation routes. Macrophage colony stimulation factor M-CSF is a common factor; bone is likely the stimulus for os …
Osteoclasts and macrophages share progenitors that must receive decisive lineage signals driving them into their respective differentiation …
587 results